The purpose of the blog is to summarize the fundamentals of the branch of Connectomics while following the textbook by Fornito et al1. Connectomics deals with quantifying, visualizing, and understanding the organization of brain networks at different scales of space and time. Since nodes and edges can be viewed as the building blocks of a network, it is important to ask the question - How do we define the nodes and edges of a brain network? It is not a straightforward question to answer due to the multi-scale spatio-temporal organization of the brain.
Spatial organization of the brain.
Figure 12 gives a pictorial depiction of the different spatial resolutions at which neuroscience models can be defined.
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A. Fornito, A. Zalesky, and E.T. Bullmore, Fundamentals of Brain Network Analysis, Elsevier (2016). ↩
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Wulfram Gerstner, Werner M. Kistler, Richard Naud, and Liam Paninski, Neuronal Dynamics: From single neurons to networks and models of cognition and beyond, Chapter 12, Available online as of 5 Dec 2023. ↩